Hi Sir/Madam Welcome to Health Care Magic I can certainly understand your concern and. Worry about the side effects of desvenlafexine side effects , as it is SNRI is serotonin norepinephrine reuptake inhibitor , due to which serotonin and norepinephrine increases which is very useful in depression. The main pathology in depression is decrease in serotonin , which causes sad mood, fatigue , lack of interest in work, sleep disturbances , decreased appetite, hopelessness, worthlessness and all, panic attacks mainly due to Norepinephrine imbalance, you have mentioned there are no further attacks ...But it is very important to continue these drugs for atleast 6-9 months even after full recovery to prevent relapse and for maintenance . There is nothing to worry much about its side effects like nausea, vomiting, gastritis ...But these are present with any drugs ...It may have diastolic hypertension but which is very rare in your age group as you are still young, so no need to worry about its side effects as it is required for the brain to balance the neurotransmitters...being a psychiatrist , I can definitely advise you to continue the above Medication for atleast 1 year for good results.Consult your psychiatrist for further follow up Post your further questions if any, I will available to take up your follow up questions Thank you