I just got home from a weekend in the hospital, went off clonidine cold turkey, .15 mg 2x day. Cardiologist recommended going back on clonidine, split the dose in 3 and start on lisinopril Is there any drug reaction between the two? I have been on clonidine 18 - 20 yrs and it has quit working. I was thinking to wean off at .25/mg/day, .2 mg/day, .15, .10, .05 on each decrease about 2 weeks.