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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Medications Required In A Pregnancy With Protein S Deficiency?

Hi, I am 31 yrs of age. I had 2 miscarriages in the past(Oct 20th 2013(6 weeks) and 15th June 2014(20weeks)). Thrombophilia report indicated Protein S deficiency. I am not yet pregnant but my doctor have started me on Ecosprin 75. Once I conceive what all medication or injections do I have to take considering Protein S deficinency? I am worried about miscarrying again.
Mon, 30 Jan 2017
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OBGYN 's  Response
Hi ,
Sorry about your bad previous history. But don.t panic, you are lucky to have a diagnosis & which can be treated.
This condition is a family of disorders called Thombophilias. Blood has a tendency to clot / thicken, so indirectly reduce blood flow to baby. So baby will have reduced growth, reduced water around it , your Blood pressure may rise & suddenly baby heart beat stops.
Before pregnancy any other member of that family of diseases has also to ruled out.
You will need Folic acid through out pregnancy. Ecospirin has to be continued till 34 weeks. You will need Inj Low molecular weight Heparin Sub-cutaneous daily once baby heart beat seen on scan till 24 hrs before delivery & to be continued after delivery , based on evaluation , to avoid DVT after delivery.
Hope I have addressed your concern
All the best
Dr.Balakrishnan
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What Are The Medications Required In A Pregnancy With Protein S Deficiency?

Hi , Sorry about your bad previous history. But don.t panic, you are lucky to have a diagnosis & which can be treated. This condition is a family of disorders called Thombophilias. Blood has a tendency to clot / thicken, so indirectly reduce blood flow to baby. So baby will have reduced growth, reduced water around it , your Blood pressure may rise & suddenly baby heart beat stops. Before pregnancy any other member of that family of diseases has also to ruled out. You will need Folic acid through out pregnancy. Ecospirin has to be continued till 34 weeks. You will need Inj Low molecular weight Heparin Sub-cutaneous daily once baby heart beat seen on scan till 24 hrs before delivery & to be continued after delivery , based on evaluation , to avoid DVT after delivery. Hope I have addressed your concern All the best Dr.Balakrishnan