my Cardiologist has me on Clonidine .1 mg twice a day and Diltiazem 240 mg once a day along with 20 mg Linsinopril. I have lost a lot of weight and my BP has been doing very well. I read that Clonidine and Diltiazem together can cause adverse reaction and can cause you to have a pacemaker put in. (Sinus bradycardia resulting in hospitalization and pacemaker insertion has been reported in association with the use of clonidine concurrently with diltiazem. Monitor heart rate in patients receiving concomitant diltiazem and clonidine.) For the past few weeks I ve had a couple of heart palpitations problems and I feel like I should be taken off something.