I am a 50 year old male with a sudden onset of joint pain, and recurring low platelet count and high MPV. Prior to this I've never had any issues, apart from being diagnosed with pre-hypertension. I am currently not on any meds.About a year ago I had a very sudden onset of joint pain. Within just a few months I had chronic pain in both my shoulders, my right hip and wrist. During the same time I could hear both my knees start "crunching", especially when getting up from a low seated position or going up stairs. Blood work over the past year, while previously normal, have consistently shown a lower than normal platelet count and a higher that normal MPV.

I have seen my GP, two rheumatologists, and a hematologist and their findings have been inconclusive.

In your opinion, with the information I gave you, what can be the cause of my symptoms? I would like to rule out cancer, tumors, etc...