Hi, Every so many months I get an ulcerative breakout in my mouth. I have taken lysine as a preventative and it seemed to keep them away for a longer time but has to be taken before the breakout. I have had two biopsies and not much help. I ve taken valtrex for a year with no help. My physician has ordered me famciclovir 500 mg three times a day and hydroxine hcl 25 mg. Also, I was given prednisone for the contact dermatitis that I just happen to have right now. I do not tolerate meds well and always try to use the holistic method because of the bad reaction. The pill was so strong i couldn t keep my eyes open. I could never take three of both in a day. Saw the ent right after the pcp and he is dumbfounded. Any ideas? Marion