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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Diarrhea In A Stage 3 Multiple Myeloma Person And Undergoing Chemotherapy?

Hi Doctor,

My father was detected to have a stage3 Multiple myeloma 45days ago and he is undergoing Chemotheraphy. He is on Tab Acivir and tab Sepmax, and a weekly injection dose of (Cytomib+Endoxan+Dexona) INJ. The third cycle was on last friday and BORTENAT 3.5mg INJ was used instead of Cytomib. He is suffering continuous diarrhea since yesterday evening(since 24hrs). The hospital remains closed on Sunday.

Can you help in any case?

Thanks a lot,
Phani
Mon, 17 Nov 2014
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Pulmonologist,  's  Response
Thanks for your question on HCM.
Diarrhoea in chemotherapy patients can be due to
1. Gut infection
2. Side effects of chemotherapy drugs.
Chemotherapy makes patient immunosuppressive and more prone to infection. So infection is first probability.
Chemotherapy drugs are cytotoxic. They may change and kill normal bacterial flora of gut. So this can also lead to diarrhoea.
Treatment consist of
1. Plenty of fluids orally. ORS (Oral Rehydration Solution).
2. Avoid junk and outside food.
3. Eat only freshly, properly food. Avoid uncooked food.
If not improve in 2-3 days better to get done stool culture.
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What Causes Diarrhea In A Stage 3 Multiple Myeloma Person And Undergoing Chemotherapy?

Thanks for your question on HCM. Diarrhoea in chemotherapy patients can be due to 1. Gut infection 2. Side effects of chemotherapy drugs. Chemotherapy makes patient immunosuppressive and more prone to infection. So infection is first probability. Chemotherapy drugs are cytotoxic. They may change and kill normal bacterial flora of gut. So this can also lead to diarrhoea. Treatment consist of 1. Plenty of fluids orally. ORS (Oral Rehydration Solution). 2. Avoid junk and outside food. 3. Eat only freshly, properly food. Avoid uncooked food. If not improve in 2-3 days better to get done stool culture.