HI A seroma may show up on follow-up imaging studies after treatment of breast cancer . So, seromas may possibly cause some initial concern about a developing ‘lesion’. However, more commonly, seromas are usually quite visible and palpable. Seromas have no relation to ‘cancer cells’ and there is no increase in breast cancer risk whatsoever. But, seromas can complicate and extend the recovery period as the serous fluid may need draining. Seromas may also increase the likelihood of ‘surgical site seroma infection‘ (SSI). Doctors will treat and monitor seromas. However, seromas are not unique to the breast, but can develop anywhere in the body after any trauma or surgery. They are also seen following radiation therapy.