I have been seeing a doctor for awhile now for stomach problems such as bloating ,tighness in stomach ,pain at 3 on scale 1-10 becoming more frequent .I had 2 gall bladder sonagrams that was negative .I am on Nexium 40 mg once daily ,ranitidine 150 mg at bedtime and bentyl 20 mg 4 times daily.I think I need further testing .My sister 2 years ago passed a way with signet cell carcinoma ,they found it to be outside her organs ,found it when she had her gall bladder taken out .She went through endoscopy and colonoscopy and found nothing .a little concerned about this!