Hello, Thanks for your query. I have gone through the details given. As it is clear that you are on multiple drugs for a number of medical conditions including T2 DM,
hypothyroidism and
depression. There are 7 drugs listed, which you are taking regularly. Of these drugs
Metformin 1000 mg twice a day, is most often very well tolerated drug. Common side effects noticed on beginning of treatment with it are mostly gastrointestinal disturbances. Which invariably stop on taking the drug with or after food. Tremors (shivering) is unlikely to happen with that drug. Among other drugs
duloxetine is more likely to cause symptoms like
restlessness, poor coordination and shivering. Even Injections Humira (
adalimumab) is the other drug which causes weakness &
dizziness. SOmetimes due to multiple medications it is very difficult to pin point which particular side effect is due to which specific drug. But Metformin is unlikely drug for shivering. As regards feeling of weakness, if both diabetes (blood glucose) uncontrolled as well as if hypothyroidism is also not well controlled, there can be fairly severe weakness as well as sleepy feeling. Since there is no mention of blood glucose levels and HbA1c% as well as TSH levels, it is difficult to know.Thanks