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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Chest Pain And Insomnia After Taking Amitriptyline 10mg?

I AM 39 YEARS OLD. I WAS TAKING AMITRIPTYLINE 1OMG QHS FOR INTERSTITIAL CYSTITIS FOR 10 DAYS. HOWEVER, I D/C TODAY BECAUSE OF TERRIBLE SIDE EFFECTS..TINGLING IN EXTREMITIES, FACE, CHEST PAIN, INSOMNIA. I WAS WONDERING HOW LONG THESE SIDE EFFECTS WILL LAST AFTER STOPPING THE DRUG?
Mon, 27 Jul 2015
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General & Family Physician 's  Response
Hello
You are advised to take AMYTRIPTYLINE 10 mg for interstitial cystitis for 10 days .
You developed many side effects .
The plasma half life of amytritylin t1/2 31 hours , while its metabolites t1/2 is 20-92 hours .
Since according to this the metabolites will remain in body for 3-4 days after stopping the drug .
But gradually side effects will vanish , so wait for 3-4 days and all side effects will disappear.
Good luck.
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What Causes Chest Pain And Insomnia After Taking Amitriptyline 10mg?

Hello You are advised to take AMYTRIPTYLINE 10 mg for interstitial cystitis for 10 days . You developed many side effects . The plasma half life of amytritylin t1/2 31 hours , while its metabolites t1/2 is 20-92 hours . Since according to this the metabolites will remain in body for 3-4 days after stopping the drug . But gradually side effects will vanish , so wait for 3-4 days and all side effects will disappear. Good luck.