My husband just recently (10/31/11) had a below the knee amputation due to a wound on his foot from a fall. He s diabetic AND a heart patient (triple bypass in 2003, stapf (? sp) infection with it ultimately resulting in sturnam removal). He came out of the anesthesia fine. . .knew who people were & could communicate well. He was in excrutiating pain (he has a high pain tolerance) so a PCA pump was put in (Methadone). He became extremely confused at this point and the PCA pump was discontinued. He s now been on oral meds (Lortab & Oxycodone) since Wednesday (11/2) afternoon, but is still VERY confused. The night before last it was determined that his hemoglobin was low & blood needed to be given. He still remained very confused yesterday. Another blood transfusion took place last night, but again he s still confused. Any suggestions?