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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Constant Fever While On Medication For HIV?

Hi, My sister is a hiv patient. her cd4 count is 70. she started medicine from St. johns Hospital since 7th July 2014. Last 5 weeks she is having continuous fever. Now she is hospitalized at St. Johns Hospital since 1 month. But they are unable to find the root cause of fever. Can you please help/suggest me for the same? REgards, Pratima 0000
Mon, 13 Oct 2014
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General & Family Physician,  's  Response
Hello
It is very difficult to establish any diagnosis when patient it taking antiretroviral treatment .
It become more important particularly when CD+4 cell counts is less than 70 /mictoL.
As you stated that , your sister in in the hospital and still her CD+4 is dramatically low , may be due to these reason in the presence of fever :
1 Patients with CD+4 Tcell counts less than 200 /micro Lare at the risk of infection with PNEUMOCYSTITIS JIROVECI. Patients dysponea , fever and non-productive cough.
Blood also shows increase level of lactate dehydrogenase.
2 Another reason of such low count may be due to CYTOMEGALOVIRUS DISEASE . Diagnosis can be confirmed by an OPHTHALMOLOGIST for retinitis .
3 Mycobacterium avium intracellulare , one indication is counts less than 70 CD+4 T cell.
Since count is very less so in HIV infected there develop "OPPORTUNISTIC INFECTION " , so as I mentioned fever may be due to above mentioned reason .
Hope this will help you in framing the future plan of treatment .
Good luck .
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What Causes Constant Fever While On Medication For HIV?

Hello It is very difficult to establish any diagnosis when patient it taking antiretroviral treatment . It become more important particularly when CD+4 cell counts is less than 70 /mictoL. As you stated that , your sister in in the hospital and still her CD+4 is dramatically low , may be due to these reason in the presence of fever : 1 Patients with CD+4 Tcell counts less than 200 /micro Lare at the risk of infection with PNEUMOCYSTITIS JIROVECI. Patients dysponea , fever and non-productive cough. Blood also shows increase level of lactate dehydrogenase. 2 Another reason of such low count may be due to CYTOMEGALOVIRUS DISEASE . Diagnosis can be confirmed by an OPHTHALMOLOGIST for retinitis . 3 Mycobacterium avium intracellulare , one indication is counts less than 70 CD+4 T cell. Since count is very less so in HIV infected there develop OPPORTUNISTIC INFECTION , so as I mentioned fever may be due to above mentioned reason . Hope this will help you in framing the future plan of treatment . Good luck .