Hi, Ovacare tablet contains letrozole which is used alone or with other treatments like surgery or radiation, to treat early breast cancer in postmenopausal women. It is also be used as the first line treatment of advanced breast cancer that has spread within the breast or to other areas of the body. Side effects of Ovacare are hot flashes, sweating, constipation, fatigue, bone, muscle or joint pain, headache, drowsiness, nervousness, shakiness, tiredness, weakness, allergic reactions etc. Sign of hot flashes like sudden feeling of heat in the body, a flushed appearance with red and blotchy skin, increased heart rate, a chilled feeling as the hot flash lets up etc is one of the most common side effects of Ovacare. It happens due to decreased estrogen levels. The frequency of flashes reduces once your body adjusts to Ovacare tablet. If these side effects persist for long or bother you, then you should consult your doctor promptly for medical help. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician