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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Daytime Sleepiness While Treating Diabetic Neuropathy?

I am on Lyrica 100 mg bid for Diabetic Neuropathy. I noticed I have been having a lot of daytime sleepiness and feel like I am in a dream state at times. I have other co-morbids such as Fibromyalgia, Sleep Apnea, T2 DM, HTN, Vitamin D deficiency. I am on other meds as well as I use my CPAP religiously. Should I let my MD know about this sleepiness and dream state?
Mon, 24 Apr 2017
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Diabetologist,  's  Response
Hello, Thanks for the query.
Lyrica- pragabalin 100 mg twice a day is quite likely to cause a good deal of drowsiness. That side effect is almost always seen with pragabalin. Reduced dosage, might help in lessening the sleepiness. It is one of the most commonly used drugs to control pain in diabetic neuropathy. You should informm your MD and find out if an alternative can be given or reduced dosage may be used. It is also very important to achieve strict blood glucose control with fasting glucose around <100 mg, PP 150 to 160 mg & HbA1c% 6.8. That will help in better relief of neuropathic pain in addition to the drugs. Thanks.
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What Causes Daytime Sleepiness While Treating Diabetic Neuropathy?

Hello, Thanks for the query. Lyrica- pragabalin 100 mg twice a day is quite likely to cause a good deal of drowsiness. That side effect is almost always seen with pragabalin. Reduced dosage, might help in lessening the sleepiness. It is one of the most commonly used drugs to control pain in diabetic neuropathy. You should informm your MD and find out if an alternative can be given or reduced dosage may be used. It is also very important to achieve strict blood glucose control with fasting glucose around 100 mg, PP 150 to 160 mg & HbA1c% 6.8. That will help in better relief of neuropathic pain in addition to the drugs. Thanks.