Hello , I have been on Cymbalta for three .weeks, for diabetic neuropathy and depression and anxiety. I also have. Cardiomyopathy. I was put on Lyrica to start off with for the above but could not urinate properly. On Cymbalta the first week I felt the happiest I have felt in a very long times then in the second week constipation set in and my urinating has decreased, I have loss my appetite , infact I have lost ten pounds in the three weeks. Ho,wever with my heart condition I am very worried about my cardiomyopathy. Will this symptoms pass or should I cease the use of this drug. Anything you could do to answer my question would be fantastic. The pain is better which is great, but this week I have felt deeply depressed and don t know if this will pass. Can you help me please? Thankyou Wanda