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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated 'anti-ds DNA Ab Qn'?

I recieved my Anti-ds Dna ab qn results and my number was 66 the lab says anything above 9 is positive, my test was repeated and my levels was 88, my ANA direct also came back positive and my hepatitis C came back reactive but i have not did a fu blood test for it, im concerned that my rheumy is beating around the bush with me because im am only 22 and she does not want to scare me, she did tell me i had SLE though, my concern is that the larger my Anti-ds Dna ab qn comes back the further long the damage is. Should i be seriously concerned? Was does Larger numbers mean i can not find anyone online w/ numbers that high, i was also test for other autoimmune test and the came back neg.
Fri, 4 Jul 2014
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Rheumatologist 's  Response
Hi and thanks for the query

I am Dr. Alok and very pleased to be assisting you with your health questions today.

Antids DNA antibody refers to high disease activity or majour system involvement like kidneys. but before reaching to any conclusion, I advice you to see your rheumatologist, who can see this report with your overall clinical pictures

Hope this helps and provides answers to your question.
If you have any further queries, please don’t hesitate to ask me again
I wish you good health, take care
--Dr. Alok
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Rheumatologist Dr. Divya Agarwal's  Response
yes high ds dna antibodies generally means a more severe disease.
however it needs to be corelated clinically.
if your symptoms are also severe then you need to be on increased doses of medication.
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What Causes Elevated 'anti-ds DNA Ab Qn'?

Hi and thanks for the query I am Dr. Alok and very pleased to be assisting you with your health questions today. Antids DNA antibody refers to high disease activity or majour system involvement like kidneys. but before reaching to any conclusion, I advice you to see your rheumatologist, who can see this report with your overall clinical pictures Hope this helps and provides answers to your question. If you have any further queries, please don’t hesitate to ask me again I wish you good health, take care --Dr. Alok