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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated Liver Enzymes In A Child?

Dear Doctor My son is 1 year and 10 months , when he was around 7 months old , I did a routine blood tests to check on his levels . the report showed that his LFT was elevated, ALT- 170 , AST-190.Doctors suggested to wait till be completes 1 year as infants levels can fluctuate. I repeated the tests in intervals of 3 months and his LFT level remained the same , no decrease. As per doctors advise I did the below tests ANA,ASMA,DS-DNA,total globulin,CBC,all virology study, Hepatitis tests, jaudince tests, G6PD,urine for amnioacid,urine for organic acid,blood for aminoacid,serumcerulo plasma, 1alpha beta protein, all these showed normal results. The PCR,EBC,CMV tests showed weak positive.My son is active and his growth is all normal . Doctor please can you confirm why his liver enzyme is still high . Do we have to do any other tests.
Thu, 8 Jun 2017
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Pediatrician 's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

As you said CMV PCR is positive that means he is having CMV infection. Most CMV infections are asymptomatic while some may have serious problems like pneumonia, sepsis like syndrome, and hepatitis.

There might be a possibility of mild CMV hepatitis. I would suggest repeat CMV PCR, IGG, and IgM tests for further confirmation.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Khan Shoeb Mohammad Sher Mohammad
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What Causes Elevated Liver Enzymes In A Child?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. As you said CMV PCR is positive that means he is having CMV infection. Most CMV infections are asymptomatic while some may have serious problems like pneumonia, sepsis like syndrome, and hepatitis. There might be a possibility of mild CMV hepatitis. I would suggest repeat CMV PCR, IGG, and IgM tests for further confirmation. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Khan Shoeb Mohammad Sher Mohammad