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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated Liver Enzymes?

I have always had normal AST and ALT reading and recently had a big jump up from normal to AST42 / ALT 40 in September to 58/88 in November and now 226/354 and 199/297 in two recent December tests. I had pneumonia following a trip to Turkey in July and have tested negative for hepatitis. Any ideas on why this sudden jump? Everything else is normal except high thyroglobulin antibodies. I also take 40mg of lisinopril daily and have a history of allergies and allergy induced migranes when I took allergy shots.
Mon, 28 Dec 2015
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Gastroenterologist,  's  Response
Hello. Thanks for putting your query in HCM.

I can understand your concerns.

Elevated liver enzymes suggest liver cell injury.

There are many causes for elevation of liver enzymes like alcohol intake, Hepatitis B and C virus, wilson disease, autoimmune liver disease and drug induced.

In your case it may be drug induced. For pneumonia I assume you have taken some antibiotics, lisinopril itsef causes elevation of liver enzymes. So I will suggest you to visit a gastroenterologist for evaluation and appropriate management
I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon.
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What Causes Elevated Liver Enzymes?

Hello. Thanks for putting your query in HCM. I can understand your concerns. Elevated liver enzymes suggest liver cell injury. There are many causes for elevation of liver enzymes like alcohol intake, Hepatitis B and C virus, wilson disease, autoimmune liver disease and drug induced. In your case it may be drug induced. For pneumonia I assume you have taken some antibiotics, lisinopril itsef causes elevation of liver enzymes. So I will suggest you to visit a gastroenterologist for evaluation and appropriate management I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon.