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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Excessive Sweating When Weaning Off Methadone?

Yes I have just switched from 100mg of Methadone a day to 75mg patch every 3 days, and I am on the 2nd day now, and I am starting to sweat, feeling like W/D or am I imaging things? It does not seem to be as strong as Methadone? Also have been on Methadone for ten years.

Thu, 27 Nov 2014
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Psychiatrist,  's  Response
Hello thanks for asking from HCM

Methadone is used in opioid dependence to prevent withdrawal effects of opioids (morphine, heroine etc.). You were on 100 mg per day and then started on 75 mg patch every three days. This has reduced a significant dose and this caused the precipitation of withdrawal. The symptoms like sedating, imagining thing, weird behaviour etc are due to withdrawal only. As per my opinion consult a Psychiatrist for treatment of withdrawal symptoms. Dose of methadone should be increased a little bit and then to be tapered again after a couple of weeks.
Second option is to start some partial agonist drug of opioids like Buprenorphin (in combination with Naloxone). This will help to smoothen the withdrawal syndrome. Once withdrawal symptoms go away then gradual tapering of doses can be done.

Thanks, hope this helps you.
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What Causes Excessive Sweating When Weaning Off Methadone?

Hello thanks for asking from HCM Methadone is used in opioid dependence to prevent withdrawal effects of opioids (morphine, heroine etc.). You were on 100 mg per day and then started on 75 mg patch every three days. This has reduced a significant dose and this caused the precipitation of withdrawal. The symptoms like sedating, imagining thing, weird behaviour etc are due to withdrawal only. As per my opinion consult a Psychiatrist for treatment of withdrawal symptoms. Dose of methadone should be increased a little bit and then to be tapered again after a couple of weeks. Second option is to start some partial agonist drug of opioids like Buprenorphin (in combination with Naloxone). This will help to smoothen the withdrawal syndrome. Once withdrawal symptoms go away then gradual tapering of doses can be done. Thanks, hope this helps you.