Hello
I have gone through your question and understand your concern.
Diphenhydramine is an antihistamine that reduces the effects of natural chemical histamine in the body.
Your daughter has taken a big too much diphenhydramine in a short period of time.This drug affect the
central nervous system and can cause sleepiness and tiredness.So,the diphenhydramine abuse can be the cause of her constant tiredness.
I didn't find in the literature any relation between diphenhydramine and
nosebleeds.
Anyway i can say that this drug is an antihistamine, which dries out a person's mouth and nasal passages and other mucous membranes.
That means when a person goes to blow their nose they can have a nosebleed and the nose may become painful.
If they have a vein or capillary very near the inner surface of the nose, the nosebleed can be spontaneous.This can explain the continually nose bleeds of your daughter.
My advice for you is to consult your daughter physician because she may
need medical help to stop the cotinually nosebleed and to start a
detoxification programme.
Hope this is helpful.
If you have other questions,feel free and ask.I will be happy to help.
Best regards.
At the other side