Hello dear user of HCM! Thank you for sharing your concerns with us! I understand the situation you are going through! Yes the general feeling of tiredness and weakness is the most common side effect of furosemide. We have to take into consideration that you take a couple of other drugs in the same time, so the possibility of side effects is quite bigger. But if you haven t had such symptoms before you started furosemide we might think that it is responsible. In this case i would recommend you to take the half of the tablet every morning and see if the side effects are gone gradually. If they don t then another diuretic drug must be taken instead of this. Since you are diabetic too, you must consult with your endocrinologist to do changes in your therapy. I hope you will be fine soon. I wish you a good health! DR ERIOL