Hello, Thanks for posting your query on Healthcare Magic... * Brief Answer: celecoxib can cause salt and water retention and lead to high blood pressure,Consult before stopping. *Explanation: My opinion is that high blood pressure on many occasions is an indication for control .That happens on many levels. First, be sure that high blood pressure is not secondary to any other diseases as Cushing or renal failure.Then ,Diet with low salt and less fat content is crucial. Exercise and other healthy activities are also a mean to control blood pressure. If all that dose not help, medications are a must .That is usually decided by your doctor according to your condition and comorbidities .Some drugs that are perfect for patients are not necessary good for others.Regular blood pressure monitoring is as important as starting treatment so that we could assess efficacy of the medication we started. I suggest my patients the following :atrial fibrillation is caused by high blood pressure , rate control and anti hypertensive, do some investigations as echocardiogram and electrocardiogram. The information provided by you is not sufficient to provide a good opinion. If someone comes to me with this condition I would ask them about degree of arthritis and if pain and inflammation is controlled *Conclusion: I suggest you consult your physician about stopping celecoxib, start blood pressure control and run other investigations needed. If you have any further questions I will be happy to help, If not, you can close the discussion and rate the answer. Wish you good health.