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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Increased WBC Count When Suffering From HIV?

My WBC count has been 6.7 on the average for 1 year and in the recent month it has gone from 16.5 a week ago and 19.7 today. I am HIV positive with cd4 of 498 viral load is 14000. Hypertension, hyperthyroid, potassium low & depression. I am not currently on HIV Meds.
Wed, 10 Dec 2014
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General & Family Physician,  's  Response
Hello
As you mentioned that your CD4+Tcell count is 498 and viral load is 14000.
You are also having many disease , mentioned in the query .
The main problem is increase in leucocyte counts from 6700 to 16500 ,further within a week 19700 cmm .
This increase is the cause of concern.
I will try to explain you , so note it carefully .
Following initial infection of HIV , the virus infects CD4+ cells , probably T LYMPHOCYTES or monocytes or bone marrow-derived dendritic cells ..
Both during this initial stage and late in infection ( as in your case , since you have taken treatment for HIV ), the LYMPHOID system is a major site for the establishment 7 propagation of HIV infection.
Now you are not taking any anti viral treatment , so this increase in W B C may be due to HIV infection ( replication ).
So I recommend you consult your HIV treating physician and get his opinion at earliest because within a gap of 7 days WBCs increases( however your CD4+ count is still under control ).
Hope this will help you.
Good luck.
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What Causes Increased WBC Count When Suffering From HIV?

Hello As you mentioned that your CD4+Tcell count is 498 and viral load is 14000. You are also having many disease , mentioned in the query . The main problem is increase in leucocyte counts from 6700 to 16500 ,further within a week 19700 cmm . This increase is the cause of concern. I will try to explain you , so note it carefully . Following initial infection of HIV , the virus infects CD4+ cells , probably T LYMPHOCYTES or monocytes or bone marrow-derived dendritic cells .. Both during this initial stage and late in infection ( as in your case , since you have taken treatment for HIV ), the LYMPHOID system is a major site for the establishment 7 propagation of HIV infection. Now you are not taking any anti viral treatment , so this increase in W B C may be due to HIV infection ( replication ). So I recommend you consult your HIV treating physician and get his opinion at earliest because within a gap of 7 days WBCs increases( however your CD4+ count is still under control ). Hope this will help you. Good luck.