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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Increased Level Of Albumin In Urine?

My last few tests for Urine Micro albumin were as follows" 3-33-1= 14, 5-06-10 = 104 12-06-10 .06 and the on 301011 it was 202, I don't understand why this bounces around so much,\. I am a 65 year old type two diabetic and my doctors didn't address this but I read it on a print out the doctor gave me, shoudl i be concerned? My wight is 130 and i am 5'4 1/2"
posted on Fri, 14 Mar 2014
Twitter Thu, 25 Dec 2014 Answered on
Twitter Fri, 26 Dec 2014 Last reviewed on
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Radiologist,  's  Response
Hi,
Thanks for writing in.

Microalbuminuria is defined as levels of albumin ranging from 30 to 300 mg in a 24-h urine collection. Overt albuminuria, macroalbuminuria, or proteinuria is defined as a urinary albumin excretion of ≥300 mg/24 h. Patients with type 2 diabetes may have microalbuminuria at presentation, as they may have had latent disease for years. A positive result should be repeated once or twice in the subsequent month and, if it is borderline, a full 24-hour urine collection will give a more definitive result. False positive results can occur after heavy exercise or with urinary tract infection.

Concern is there in following patients
Younger patients (less than 55 years).
Those with evidence of progressive kidney disease (eGFR declining at more than 4 mls/min/year), after confirmation with a second blood test.

Since you are elderly and with no significant altered blood tests, it is not a concern. Please do not worry.
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What Causes Increased Level Of Albumin In Urine?

Hi, Thanks for writing in. Microalbuminuria is defined as levels of albumin ranging from 30 to 300 mg in a 24-h urine collection. Overt albuminuria, macroalbuminuria, or proteinuria is defined as a urinary albumin excretion of ≥300 mg/24 h. Patients with type 2 diabetes may have microalbuminuria at presentation, as they may have had latent disease for years. A positive result should be repeated once or twice in the subsequent month and, if it is borderline, a full 24-hour urine collection will give a more definitive result. False positive results can occur after heavy exercise or with urinary tract infection. Concern is there in following patients Younger patients (less than 55 years). Those with evidence of progressive kidney disease (eGFR declining at more than 4 mls/min/year), after confirmation with a second blood test. Since you are elderly and with no significant altered blood tests, it is not a concern. Please do not worry.