Hello Mr.Umesh, Thanks for posting your query. I have gone through it and understood your concern. The possible causes for delayed menstrual cycle of your wife are pregnancy, hormone imbalance which can be due to the weight gain, poorly controlled hypothyroid state, stress, infections of the genito-urinary tract and cysts on the ovary or other hormone imbalances. I would ask her to get a clinical evaluation, a sonogram of the pelvis preferably in the trans-vaginal route, a complete hormone assay to clarify. Further management can be planned accordingly. Maintenance of a healthy lifestyle is essential. Hope this helps.