Every three months since October, I have had what seems like an allergic reaction to "something." All of a sudden my lips begin to itch, my left nostril itches, my vagina uncontrollably itches and my tailbone itches. This lasts for 20-30 minutes. And then the swelling begins. The next morning, when I wake up, the left side of my lips will be extremely swollen, as well as the left side of my nostril. My vagina and tailbone will itch and seem inflamed, also. This usually lasts for 3-4 days and is painful and irritating. I am 46 years old. I am 5'4" and weigh 140 lbs. I am in pretty good physical health. Could this be early menopause? I have seen my gyno and he referred me to an ear, nose and throat specialist and they are both "at a loss." What do you think?