Hello, Your health of the gum and bone is a very important factor for maintaining your teeth. There is more tooth loss, commonly, due to lack of supporting bone than decay. Have you been to a periodontist? Periodontal disease is a progessive disease and preventive measures are important for keeping your teeth. I need more information on your dental health history. Have you keep up with routine cleanings and exams? Have you had a history of a high rate of decay, abscesses or gum treatments? Overall health changes affect the oral environment. Medications have side effects. Dry mouth is a common side effect and causes an increase in decay and inflammed tissue. Your dentist can help address your individual conditions and make suggestions. Rinse with warm salt water and maintain good daily dental care. Your immune system definitely influences the oral environment. Your dentist will consider this when making dental care recommendations. Keep up with a nutritious diet, balanced vitamins and keep well hydrated. Opportunistic infections are a risk in your mouth. Imbalances can cause common infections such as Thrush. Thank you for your inquiry. I hope my suggestions have been helpful. I am glad to answer additional questions.