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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Low BUN To Creatinine Ratio?

Hi. I drank heavily for a few years in my early 20 s. Today I had bloodwork done and a urine panel. Only abnormalities were BUN to creatinine ratio: BUN 4, Creatinine 0.5, so a ratio 8:1. I was advised this was unimportant because all other results, AST, ALT, Bilirubin, Albumin, protein etc. were normal. AST to ALT ratio normal as well. Reading online the low BUN to creatinine ratio can be an indicator or cirrhosis. I have read the liver enzymes and other aforementioned lab results may come back ideal and one may still have some form of liver disease or cirrhosis. Is it realistically possible this BUN creatinine ratio can indicate liver problems worth investigating in the absence of other blood and urine abnormalities? I am obese, 200 lbs. at 5 5 and 29 year old female. Thank you.
Thu, 7 May 2020
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Internal Medicine Specialist 's  Response
Hello,

Low BUN-to-creatinine ratio may be caused by a diet low in protein, a severe muscle injury called rhabdomyolysis, pregnancy, cirrhosis, or syndrome of inappropriate antidiuretic hormone secretion (SIADH) etc.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr. Penchila Prasad Kandikattu
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What Causes Low BUN To Creatinine Ratio?

Hello, Low BUN-to-creatinine ratio may be caused by a diet low in protein, a severe muscle injury called rhabdomyolysis, pregnancy, cirrhosis, or syndrome of inappropriate antidiuretic hormone secretion (SIADH) etc. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr. Penchila Prasad Kandikattu