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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Low Testosterone?

My husband has low testosterone, and has been given medicine to help with his levels. He's been using androgel for 2 yrs, and his levels are not improving like they should. His average levels are 130. What could be causing his low levels? He is 34 yrs old, and weighs 220
Mon, 22 Sep 2014
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Urologist,  's  Response
Hi
At his body weight there is also a possibility that his body might be converting his own testosterone to estradiol. And this could be the reason why his t levels ate not rising despite treatment. Please get his estradiol E2 levels checked and if they are high he should be started on drugs called aromatade inhibitors which should help improve testosterone levels.
Another option would be to have a depot dose of testosterone once every 6-12 weeks for better and sustained results rather than the gel.
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What Causes Low Testosterone?

Hi At his body weight there is also a possibility that his body might be converting his own testosterone to estradiol. And this could be the reason why his t levels ate not rising despite treatment. Please get his estradiol E2 levels checked and if they are high he should be started on drugs called aromatade inhibitors which should help improve testosterone levels. Another option would be to have a depot dose of testosterone once every 6-12 weeks for better and sustained results rather than the gel.