hi dear thanks for your query I would be happy to help you Firstly i want to tell you that monoclonal gammopathy is a disease of immunoglobins ; in simple term antibodies . The following preliminary investigation has to be done to confirm your diagnosis: 1. CBC with PBS (routine blood count with peripheral blood smear) 2. Calcium level (increased) 3. Creatinine level (increased) 4. X-ray of the spine and chest (bony lytic lesions) 5. Bone marrow aspiration and biopsy (increase in plasma cells) 6. serum protein electrophoresis (M band seen). You need to do these tests as early as possible. Kindly share your reports once you receive them. Hope this helps. Thank you Follow up questions will be appreciated. Regards Dr Pallavi jain