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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Muscle Spasms While On Donepezil And Coumadin?

I am taking 10mg of Donopezil to help with my memory loss. I have been having moderate to severe muscle spasms for the past month. I have been taking this for approximately 5 months. The only other medication I take is Coumadin which I have been taking since November 2017 due to a deep vein thrombosis in my right ankle. The thrombosis has cleared but my hematologist wanted me to stay on Comadin til I am rechecked in June. Any suggestions would be appreciated. I am 80 years young. I do 1 hour of yoga a day and cycle 10 miles 5 days a week. I also do some strenuous yard work clearing brush and small trees 3 to 4 days a week getting ready for a builder to start building our new home. Thank you.
Wed, 27 Jun 2018
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Internal Medicine Specialist 's  Response
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Neither Donopezil nor Coumadin causes muscle spasm as side effect.Your muscle spasm is due to your strenous physical activity( cycling 10 miles 5 days a week).Check your serum electrolytes to rule out any Hyponatraemia.

Hope I have answered your query. Let me know if I can assist you further.
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What Causes Muscle Spasms While On Donepezil And Coumadin?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Neither Donopezil nor Coumadin causes muscle spasm as side effect.Your muscle spasm is due to your strenous physical activity( cycling 10 miles 5 days a week).Check your serum electrolytes to rule out any Hyponatraemia. Hope I have answered your query. Let me know if I can assist you further.