Hi, thanks for posting your concern in the HCM. Presence of protein and red cells in urine may not be a mere urinary tract infection. In case of culture negativity, the suspicion rises further. You should do a 24 hr urine protein test to find out whether there is significant proteinuria. Normal urine protein excretion is 150 mg/day. Persistent proteinuria with urine protein more than 500 mg /d is suggestive of glomerular disease . However, different systemic diseases, proliferative or non-proliferative glomerulonephritis may present like this. A detailed history, clinical examination and relevant investigations are needed to rule out all the differential diagnoses.Again loss of appetite, nausea, intolerance to fatty food may also suggest a liver, gall bladder or pancreatic pathology. Some other conditions including malabsorption syndrome or infections should also be excluded. Even a chronic kidney disease or an autoimmune disease may present in a similar manner. You should consult a specialist in internal medicine and a consultant nephrologist for further evaluation and management. For any further questions, please write back to us. Regards. Dr. Kaushik