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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

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What Causes Recurring E Coli Infection Of UT While Having Diabetes?

Dear Doctor, I am 58 years old and known diabetic. Have been getting repeated infection of E Colli of the Urinary Tract, inspite of Anti Biotic Injections through IV. Could you please suggest a sure cure for this, as this has badly effected my kidney. My sugar levels are under control. Regards.
Fri, 31 May 2019
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General Surgeon,  's  Response
Hello,

There are many reasons for the recurrent E.Coli infection in a patient with diabetes as
- different strains of E.Coli than the previous infection as it has very high antigenic specificity and variability through its pili over the surface.
- the problem in the phagocytosis through glycosylation in the glomeruli of the kidneys due to diabetes
- consumption of compliments from the glomerulopathy and hence the bacteria can flourish more easily
- lack of hydration level adequacy
- sexual intercourse related if active

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Bhagyesh V. Patel, General Surgeon
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What Causes Recurring E Coli Infection Of UT While Having Diabetes?

Hello, There are many reasons for the recurrent E.Coli infection in a patient with diabetes as - different strains of E.Coli than the previous infection as it has very high antigenic specificity and variability through its pili over the surface. - the problem in the phagocytosis through glycosylation in the glomeruli of the kidneys due to diabetes - consumption of compliments from the glomerulopathy and hence the bacteria can flourish more easily - lack of hydration level adequacy - sexual intercourse related if active Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Bhagyesh V. Patel, General Surgeon