Hello, As what I understand from your history that there is a pain in the wrist, thumb, and doing wrist extension. You can please provide some more information like the nature of the job you do and is this the first time the symptoms have arises or it was there in the past. What it appears from the history is that this could be related to the carpal tunnel and the flexor retinaculum which covers the tunnel is getting tight which is leading to compression over the vessels beneath it. You should try taking TENS therapy and ultrasound therapy at a Physical therapy clinic and perform some slow stretching exercises. Also, massage in a slow and gradual manner will help release the tightness. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Jay Indravadan Patel, Physical Therapist or Physiotherapist