My 14 year old daughter has a long history of abdominal pain, with Celiac Disease ruled in then out at age 5. She is controlled on Miralax daily for years. Recent repeat of Celiac blods was negative. She is now 14, lost her periods 5 months ago, started more severe abdominal pain 3 months ago, and it is now very severe mid region pain, loss of appetite, constipation, fatigue and 7 lb weight loss in 2 months. We are waiting for specialist appt. Do you have any ideas of differential diagnoses?