Found left testicle shrunk severly tonight. Penis smaller.. I was amazed at how much the testicle has shrunk. I've diagnoses of Relapsying Polychondritis, Myasthenia Gravis and Neuropathy, Taking prednisone 20mg day, testostorone gel, methotrexate by injection, plaquinel, 30mg Oxycontin 2day.Naprosyn 1000mg day Can shrunken testicle be cancerous?