hello i appreciate your concern low metabolism may be responsible for weight gain due to thyroid or liver disease ; you need to boost your metabolism by regular exercise and having healthy diet, and living a healthy life style. I would suggest you following guidelines have small and frequent food more of fruits and steamed vegetables avoid junk, fatty and fried food or carbonated drinks don t go to bed immediately after food keep a gap for at least 2 hours don t take heavy food at night consume more of whole grains and dietary fibers You should consult your doctor for Yoga which will be very beneficial in weight reduction by boosting your metabolism. I hope you will find this information useful and relevant to your health wishing you a very good health and vitality