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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Swelling In The Ankles While On Zithromycin?

YYYY@YYYY question...my ankles are swelling...i am taking zithromycin 250 mg for upper respitory infection...i also started taking amlodopine two weeks ago for high bp....which or is it a combo causing the swelling....I see that amlodopine does cause swelling, but it started when I started the zithromycin/. thank you
Tue, 20 Feb 2018
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General & Family Physician,  's  Response
Hi & Welcome.
Side effect of Amlodipine.

Based on the history you seem to have developed ankle edema (swollen ankles) apparently caused by the blood pressure lowering medication Amlodipine ( a calcium channel blocker) which is also known to cause constipation, flushing, and increased heart rate.

The Zithromycin is generally a safer antibiotic commonly prescribed to treat susceptible infections like upper respiratory infection. However, it may cause vomiting, abdominal cramps and diarrhea.

It is not known to cause edema (swollen ankles).

I advise you to consult your treating doctor for an alternate effective but a safer medication to control the high blood pressure.

Hope I could answer your query.
A feed back is appreciated.
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What Causes Swelling In The Ankles While On Zithromycin?

Hi & Welcome. Side effect of Amlodipine. Based on the history you seem to have developed ankle edema (swollen ankles) apparently caused by the blood pressure lowering medication Amlodipine ( a calcium channel blocker) which is also known to cause constipation, flushing, and increased heart rate. The Zithromycin is generally a safer antibiotic commonly prescribed to treat susceptible infections like upper respiratory infection. However, it may cause vomiting, abdominal cramps and diarrhea. It is not known to cause edema (swollen ankles). I advise you to consult your treating doctor for an alternate effective but a safer medication to control the high blood pressure. Hope I could answer your query. A feed back is appreciated.