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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Swollen Feet And Ankles?

Hello. I was wondering if you could tell me if increased doses of metformin are dangerous (2000 mg of Extended release daily). My last Hemoglobin A1c was 8.3 and my physician increased my dose - since then I have been having some left flank discomfort (not really pain - thought it was maybe how I was sleeping, but it hasn t gone away). I have an appointment next month, but now I ve noticed that my feet and ankles are becoming swollen daily and I fear kidney disease. Any chance the metformin is the culprit, or is it possible that my disease is advancing and I may have to add in another pharmacologic agent?
Thu, 16 Aug 2018
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General Surgeon,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

You can simply do a renal function test and check whether the status of your kidney is abnormal or not. Long standing diabetes can cause edema of foot. Very high doses of Metformin is not good for kidney. If you can’t control blood sugar level with Metformin, it is better to switch to insulin. Insulin is a better option, especially in patients with coexisting kidney disease.

Wishing you good health.

Thanks.
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What Causes Swollen Feet And Ankles?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. You can simply do a renal function test and check whether the status of your kidney is abnormal or not. Long standing diabetes can cause edema of foot. Very high doses of Metformin is not good for kidney. If you can’t control blood sugar level with Metformin, it is better to switch to insulin. Insulin is a better option, especially in patients with coexisting kidney disease. Wishing you good health. Thanks.