You are very anemic and your platelets are critically low. This could be related to the rheumatoid arthritis causing a problem with your bone marrow. Diseases like RA are autoimmune, which means your body builds antibodies against itself. Sometimes the antibodies can affect the cells in the bone marrow that produce the different types of blood cells. All your major blood cell lines appear to be affected. That is why your doctor is requesting the transfusions of blood and platelets. If you are otherwise feeling okay, this probably has been going on for a long time. A person with the degree of anemia you have is usually very symptomatic if it s developed fairly quickly. The colonoscopy is to rule out intestinal bleeding which can occur without symptoms and gradually cause severe anemia. But that would not explain the low platelets and white count. The colonscopy is advisable, but I would also recommend other blood tests to see what else might be causing the anemia and other abnormalities. You might need to have a bone marrow test. Ask about seeing a hematologist who is the specialist best suited to figure this out. Hope this answers your query. If you have further questions, I would be happy to answer them.