Sir, I am 33yr old, male, 53 kg, 154 cm, a case of HUS induced ESRD, on hemodialysis for last six years. Today i had chills with joint pain specially on knee and ankle joints during dialysis and so i had avil inj. and then i was about to loss consciousness for atleast an hour though my vitals maintained. It happened for the first time, never happened before like this. Would be grateful for responding