Last night, I had redness at the base of my toes on both feet. It looked like it might be an allergic reaction to something. I put Benadryl cream on it and went to bed. This morning, my left foot - at the base of my second toe - has three sizeable blisters or bubbles , where the redness was. They don t hurt or itch. They are not the kind of blister you get from using a rake without gloves, for example. They are not athlete s foot. They are opaque, slightly amber, and tough . They don squish.