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What Could Be The Underlying Cause Of Abdominal Pain, Ascites, And Elevated CA-125, ESR, And CRP Levels?
A sports Woman (70+ years of age) had abdominal pain with mild to moderate ascites with streakiness and nodularities in omental fat - to rule out granulomatous etiology/ peritoneal carcinomatosis, as per CT Scan Report. No pleural effusion or significant mediastinal node is noted. CT Scan report also indicated focal fibroatelectatic densities and mild bronchial wall thickening involving the lungs without any mass lesion, consolidation, or nodule. No pleural effusion or significant mediastinal node is noted. Mild fatty changes and early volume redistribution involving the liver. The pancreas shows fatty changes. No renal or ureteric calculus or hydronephrosis is seen. Intermediate widening of endometrial low attenuation with an isodense component in the cavity, (These need further evaluation, as suggested in the CT Scan report). In her blood test reports, ESR reads 55 mm/ hr. CA-125 reads 335.8 U/ml. Alpha FETO Protein 2.24 TU/ml. C-Reactive protein 44.03 mg/L. Iron (photometry) 39 M(mu)/g..... I m looking for advice on the course or treatments.......
As per your report, streakiness and nodularities in the omental fat, as well as presence of mild to moderate ascites, are not normal features. Also, as your CA125 is very high (normal being up to 35). Your ESR as well as CRP are also on higher side.
Hence in your case, it is necessary, to be further investigated for any granulomatous or cancerous etiology and particularly for ovarian / liver cancers or other etiology like granulomatous or metastatic lesions in the lungs.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Satnarain Bansal, General & Family Physician
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What Could Be The Underlying Cause Of Abdominal Pain, Ascites, And Elevated CA-125, ESR, And CRP Levels?
Hi, As per your report, streakiness and nodularities in the omental fat, as well as presence of mild to moderate ascites, are not normal features. Also, as your CA125 is very high (normal being up to 35). Your ESR as well as CRP are also on higher side. Hence in your case, it is necessary, to be further investigated for any granulomatous or cancerous etiology and particularly for ovarian / liver cancers or other etiology like granulomatous or metastatic lesions in the lungs. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Satnarain Bansal, General & Family Physician