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Dr. Andrew Rynne

Family Physician

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What Could Increase Liver Enzymes Apart From Hepatitis In Pregnancy?

Last Tuesday I had vomitting, diarrhea, and stomach pains. (I was 27 weeks currently 28 weeks pregnant) they gave me an IV so I could be hydrated, and said my liver enzymes were high. My OB is having them retested. Other than hepatitis (I've had my prenatal panel) is there anything that could cause the increase in liver enzymes?
Sat, 7 Dec 2013
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  User's Response
HI
Thank for asking to HCM
The disturbances in parenchymal cells, like inflammatory process, destruction,necrosis, and these can happens due to infections either viral bacterial parasitic, trauma could also does the same thing to cell either exogenous or endogenous, these are the likely causes responsible for liver enzyme elevation, it is wide gate open pathology for liver cell it is very fragile, hope this could help you clearing your doubts have nice day.
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General & Family Physician Dr. Muhammad Ali Safdar Khan's  Response
Hello

Thank you for your question

I am sorry for the difficult situation you are going through.

Your symptoms can easily be attributed to the lab findings. The most common causes for abnormal Liver function tests during third trimester can be HELLP syndrome (a complication associated with pregnancy and considered a variant of pre-eclampsia) and AFLP (Acute fatty liver of pregnancy).

Here are two links that be interesting for you
http://www.nlm.nih.gov/medlineplus/ency/article/000890.htm for HELLP
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538964/ for AFLP

Another possible cause for abnormal liver function tests in the last trimester can be Cholelithiasis of pregnancy.

The exact cause for either of the conditions mentioned above is not defined although there are possible causes mentioned.

Hopefully this answered your question and helped you understand the situation :)

Regards
Dr Ali
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What Could Increase Liver Enzymes Apart From Hepatitis In Pregnancy?

HI Thank for asking to HCM The disturbances in parenchymal cells, like inflammatory process, destruction,necrosis, and these can happens due to infections either viral bacterial parasitic, trauma could also does the same thing to cell either exogenous or endogenous, these are the likely causes responsible for liver enzyme elevation, it is wide gate open pathology for liver cell it is very fragile, hope this could help you clearing your doubts have nice day.