What Does Calcified Granuloma Lesion In Brain Mean And How Does It Effect?

Hi, welcome to our site. I am Dr Saumya Mittal, MD. Read your query. That is a very significant question and i appreciate your problem. I will try my best to answer your query A granuloma is where an infection may have happened once, as your doctor said, in the last 10 years or before. This infection could have been anything like a tuberculosis to maybe some minor lesion. Now the body fights infections on its own. So the infection may have never come to the surface. But the body must have fought off the infection. However some damage may have been left back. Now the body usually responds by depositing calcium in such spots- whether in brain, or in any other body part. This deposition occurs over a long period of time- hence we say maybe the infection occurred 10 years back. The lesion in itself is inactive. The problem however is that it is in brain. So if the lesion is calcified in brain, especially in cortex, it makes her prone to seizures. The brain works on electrical signals. The calcific spot forms a lesion that changes this electrical field and makes it abnormal. This abnormal electrical field may be going on, and may be under control. But with right set of conditions, a seizure can develop- This set of conditions can include- a lack of sleep excess coffee/tea staring at blinking lights too long too long television gazing etc Brain surgery should be avoided as far as possible. However you can discuss with the doctor the need of prophylactic antiepileptic drugs. Personally, I would avoid them till at least the first seizure episode. Before that just avoid the triggers. Testing a Mantoux test, ESR, TB Quantiferon gold test may help. I hope this helps you. Inform the reports mentioned above/if any other so I can be of help further. I have given you the answer to the maximum considering the information provided. The results of the tests could further enhance my answer to you. Please do understand that some details could be extracted from a detailed history and examination. Please feel free to ask another query. I would be glad to help you. Looking forward to your return query with the details asked so that I can help you further. (If the answer has helped you, please indicate this) Best of luck. Dr Mittal. MBBS, MD (Internal Medicine), CC (Diabetes Mellitus), DNB (Neurology) Consultant Physician and Diabetologist JS Hospital Ex Apollo Hospital, Delhi Ex Kailash Hospital, Noida