Hi,I am Dr. Aniruddha Malpani (Infertility Specialist). I will be looking into your question and guiding you through the process. Please write your question below.
What Does Decrease In Acrosome Positive Reaction Indicates The Possibility Of Low Fertilization Mean?
Total Ejaculate Millions 203 million Total Ejaculate: Normal (5th per: 40 75th per: 120) Sperm Conc. (millions / ml) 58 mill/ml MOTILITY ASSESSMENT (5th percentile value) Sperm Motility 1 Hr 2 Hrs Total Progressive 30% 10% Non Progressive 05% 02% Immotile 65% 88% Total motility (Total Progressive + Non Progressive) 35% 12% 1 Hour Total motility: Sub Normal (5th Per: 42 75th Per: 50) Advanced CASA parameters Micro mt/sec Straight Line Velocity-VSL Not assessed Curvilinear Velocity –VCL Not assessed Hyper activation –H max assay Not assessed Advanced Total Progressive Motility Assessment (CASMA) Rapid Progressive 02% Slow Progressive 28% Advanced Total progressive motility: Sub Normal (5th Per: 10 75th Per: 15) MORPHOLOGY ASSESSMENT (TYGERBERG KRUGER) (5th percentile value) Morphology % Normal Forms 04% Over all Defects 96% Sperm Morphology: Normal (5th Per: 4 75th Per: 9) Head Defects 59% Mid Piece and Neck Defects 20% Tail Defects 04% Multiple Defects 13% Excessive residual cytoplasm (ERC) 09% Ex. residual cytoplasm: Not Significant ADDITIONAL PARAMETER ASSESSMENT: Round cells: 02/hpf Bacteria: Not Significant RBC: Nil Agglutination: Nil Cellular debris: Not Significant Comments if any: SPERM FUNCTIONAL INTEGRITY ASSESMENT – SFI Flagellar Integrity - Hypo Osmotic Swelling 53% Osmotic Swelling Test Normal : 55 % spermatozoa with tail coiling Significance : This test is a good index of healthy spermatozoa. Clinical Relevance : Decrease in HOS positive reaction indicates loss of viability Hence may be an indication of degenerative changes occurring Spermiation defects - Acrosome Reaction after Ionophore Challenge 12% ARIC Test Normal : 15 % spermatozoa with halos having mean diameter of 10 µm Subnormal : 10-15 % spermatozoa with mhalos having mean diameter of 10 µm Abnormal : Significance: This test evaluates the functional status of sperm acrosome and is a good indicator of sperm’s ability to penetrate the oocyte. Clinical Relevance: Decrease in Acrosome positive reaction indicates the Possibility of low or nil fertilization Can you please help understand the report
Hello dear, poor ability of sperm to penetrate means inability of sperm to fertilise ovum and thus failing to achieve a successful pregnancy eventually. This is the theoretical part of your answer but I will be able to guide u better if I have some points of your history like : why were you advised semen analysis : your age : how long have you been married : smoking and drinking habits
Till then as far as this report is concerned - your sperm count is good but motility is average and there is poor acrosome action, chances of spontaneous conception are still there but definitely decreased.
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What Does Decrease In Acrosome Positive Reaction Indicates The Possibility Of Low Fertilization Mean?
Hello dear, poor ability of sperm to penetrate means inability of sperm to fertilise ovum and thus failing to achieve a successful pregnancy eventually. This is the theoretical part of your answer but I will be able to guide u better if I have some points of your history like : why were you advised semen analysis : your age : how long have you been married : smoking and drinking habits Till then as far as this report is concerned - your sperm count is good but motility is average and there is poor acrosome action, chances of spontaneous conception are still there but definitely decreased.