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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does High Anti TPO Mean?

My wife is into the 12th week of pregnancy. Some blood tests revealed a thyroid related problem. We did a FT4, FT3, total TSH and Anti-thyroid peroxidase antibodies test and here are the results. FT4 - 0.97 ng/dL, FT3 - 2.41 pg/mL, TSH - 0.63 uIU/mL and Anti TPO antibodies - 1300. what does this high Anti TPO mean?
Mon, 15 Dec 2014
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Endocrinologist,  's  Response
Hi Arunodaya neerati,

Welcome to HCM. I have gone through the question and understand your concerns.

There are 2 anti thyroid antibodies. Anti TPO and anti TG.

Anti TPO antibodies are anti thyroid peroxidase antibodies- which are elevated in Hashimoto's disease. Elevated antibodies means you are at risk of developing Hashimoto's hypothyroidism. At present the thyroid function is normal and no treatment is needed. But she may develop hypothyroidism in future.

In this type of cases what I do is to do thyroid function tests every 6-12 months and start treatment only when thyroid function shows hypothyroidism.

Hope I have answered your questions. If you have any further queries I will be happy to help you.

Regards,

Dr Ajish TP [MD,DM]
Consultant Endocrinologist
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What Does High Anti TPO Mean?

Hi Arunodaya neerati, Welcome to HCM. I have gone through the question and understand your concerns. There are 2 anti thyroid antibodies. Anti TPO and anti TG. Anti TPO antibodies are anti thyroid peroxidase antibodies- which are elevated in Hashimoto s disease. Elevated antibodies means you are at risk of developing Hashimoto s hypothyroidism. At present the thyroid function is normal and no treatment is needed. But she may develop hypothyroidism in future. In this type of cases what I do is to do thyroid function tests every 6-12 months and start treatment only when thyroid function shows hypothyroidism. Hope I have answered your questions. If you have any further queries I will be happy to help you. Regards, Dr Ajish TP [MD,DM] Consultant Endocrinologist