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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does Protein Level Of 45 Indicate?

My son, 13 months old, had lab work done to determine whether or not he has his dads hereditary protein c defieciency. Everything came back normal except for his protein s level. It was 45, the normal range for this hospitals lab is 65-100. My son s doctor is unfamiliar with this lab and said she would research it and get back to us. Can you please help us? Does his level of 45 mean he has protein a deficiency or does it still have time to rise to normal levels? Thank you.
Fri, 23 Jan 2015
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General & Family Physician,  's  Response
Hello,Welcome to the HCM
Thankyou for your question
Immunologic methods for the measurements of protein C include enzyme linked immunosorbant assay (ELISA) ,radioimmunoassay and electroimmunoasay.Normaly in adults it approximates 70 to 140 percent of protein C antigen level of whole pooled plasma level.
But in infants total protein is normaly at lower level as compare to adults.And Also infants and neonates have lower levels of protein C than their adult counterparts,therefore age based normal ranges must be derived separatly for the children.
Hopefully my answer will be helpfull .
Regards,Dr.Maheshwari
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What Does Protein Level Of 45 Indicate?

Hello,Welcome to the HCM Thankyou for your question Immunologic methods for the measurements of protein C include enzyme linked immunosorbant assay (ELISA) ,radioimmunoassay and electroimmunoasay.Normaly in adults it approximates 70 to 140 percent of protein C antigen level of whole pooled plasma level. But in infants total protein is normaly at lower level as compare to adults.And Also infants and neonates have lower levels of protein C than their adult counterparts,therefore age based normal ranges must be derived separatly for the children. Hopefully my answer will be helpfull . Regards,Dr.Maheshwari