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What Does The Presence Of An Anti-e Alloantibody In The Blood Test Mean, And How Might It Affect Future Blood Transfusions?
My wife received the following from a recent blood test? What does it mean? Anti-e Comment: Antibody identification studies demonstrated that the patient has an anti-e alloantibody. This alloantibody may cause hemolytic transfusion reactions or hemolytic disease of the fetus and newborn (HDFN). Red cell units lacking the corresponding antigen will be provided for future transfusions (approximately 2% of donor units). The presence of this antibody may cause delays in the provision of compatible blood for transfusion.
Sat, 29 Mar 2025
Hi,
Anti-e-alloantibody are the antibodies against an antigen, which is not present in the RBC of a person. However, these antibodies will react against antigen E, if the person receives the blood of any person, who is having antigen E on his RBC.
Therefore, such persons should be cautious, that they do not receive the blood of any donor, having these antigens in their blood. This may cause a destruction of the transfused RBCs, which may be fatal. Also, if a fetus is having this antigen (Received from father), it may cause hemolytic disease of fetus and new born.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Satnarain Bansal, General & Family Physician
Anti-e-alloantibody are the antibodies against an antigen, which is not present in the RBC of a person. However, these antibodies will react against antigen E, if the person receives the blood of any person, who is having antigen E on his RBC.
Therefore, such persons should be cautious, that they do not receive the blood of any donor, having these antigens in their blood. This may cause a destruction of the transfused RBCs, which may be fatal. Also, if a fetus is having this antigen (Received from father), it may cause hemolytic disease of fetus and new born.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Satnarain Bansal, General & Family Physician
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